Convenient synthesis of new polysubstituted isoindole-1,3-dione analogues
نویسندگان
چکیده
منابع مشابه
Convenient synthesis of nucleoside and isonucleoside analogues.
[reaction: see text]. A very simple methodology to stereoselectively achieve tricyclic isonucleosides (nucleobase = thymine, uracil, and 5-fluoruracil) and 3'-C-branched nucleosides (nucleobase = theophylline) was performed by means of a DBU-mediated addition process using a readily available 2-bromo sugar. The mechanism for these transformations implies the loss of both substituents at C-2 and...
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In the title compound, C(16)H(13)NO(2), the 2,3-dimethyl-phenyl group and the 1H-isoindole-1,3(2H)-dione group are essentially planar, with r.m.s. deviations of 0.006 and 0.013 Å, respectively, and are oriented at an angle of 78.19 (3)° with respect to each other. In the crystal, weak C-H⋯O inter-actions link the mol-ecules, forming a zigzag chain parallel to the b axis. Futhermore, C-H⋯π inter...
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ژورنال
عنوان ژورنال: TURKISH JOURNAL OF CHEMISTRY
سال: 2014
ISSN: 1300-0527,1303-6130
DOI: 10.3906/kim-1310-30